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Annual figures as reported in 10-K / 20-F / 40-F filings.
MIST · CIK 0001408443

Milestone Pharmaceuticals Inc.

Annual figures as reported, FY2017–FY2025. Ratios and growth rates derived on-page.

MIST logo
Pharmaceutical Preparations
Company profile
Nasdaq · MISTHQ Montreal, Quebec, CanadaIncorporated in A8Fiscal year ends Dec 31Non-accelerated filer Smaller reporting company
Net income
−$63.1M
▼ −51.9% vs FY2024
Free cash flow
−$49.3M
▼ −70.8% vs FY2024
Diluted EPS
−$0.75
▼ −11.9% vs FY2024

Net income

Losses shown in terracotta

−60M−40M−20M0’18’20’22’24’25−$63.1M

Recent quarters

momentum · last 12 quarters
Net income — Mar ’26 quarter
−$26.1M
▼ −25.6% vs Mar ’25
Diluted EPS — trailing 12 months
−$0.64
▲ +16.9% vs Mar ’25

Quarterly net income

Losses shown in terracotta

−20M−10M0Jun ’23Dec ’23Jun ’24Dec ’24Jun ’25Dec ’25Mar ’26−$26.1M
QuarterRevenueRev. YoYGross marginNet incomeNet marginDiluted EPS
Mar ’26———−$26.1M—−$0.20
Dec ’25———−$17.4M—−$0.12
Sep ’25———−$11.9M—−$0.12
Jun ’25———−$13.0M—−$0.20
Mar ’25———−$20.8M—−$0.31
Dec ’24———−$12.4M—−$0.18
Sep ’24———−$9.4M—−$0.14
Jun ’24———−$9.4M—−$0.14

Profitability & returns

quality of earnings

Returns on capital

Net income vs year-end equity and assets

-300%-200%-100%0%’18’20’22’24
Return on equityReturn on assets

Cash flow

cash generation

Free cash flow

Operating cash flow less capital expenditure

−40M−20M0’18’19’22’23’24’25−$49.3M

Operating cash flow

Net cash from operations

−40M−20M0’18’20’22’24’25−$49.0M

Balance sheet

financial position

Stockholders’ equity

At fiscal year end

050M100M’17’19’21’23’25$41.8M

Net debt

Long-term debt less cash — negative means net cash

−100M−50M0’19’23’24’25−$15.9M

Key ratios

derived per fiscal year
Fiscal yearROEROACurrent ratioDebt / equity
FY2025−151.0%−55.5%8.01×1.37×
FY2024−315.8%−55.0%9.10×4.06×
FY2023−355.9%−79.3%10.11×2.97×
FY2022−88.0%−78.4%11.70×—
FY2021−38.1%−35.8%17.55×—
FY2020−34.9%−33.3%24.14×—
FY2019−48.1%−44.7%14.71×0.00×
FY2018−27.8%−26.3%19.42×—
FY2017————

Annual figures

as reported
Fiscal yearRevenueGross profitOp. incomeNet incomeDiluted EPSOp. cash flowCapexTotal assetsLiabilitiesEquityCashLT debt
FY2025——−$62.1M−$63.1M−$0.75−$49.0M$302K$113.6M$71.8M$41.8M$73.0M$57.2M
FY2024——−$42.1M−$41.5M−$0.67−$28.8M$33K$75.5M$62.4M$13.1M$25.3M$53.4M
FY2023——−$61.1M−$59.7M−$1.39−$46.4M$112K$75.2M$58.5M$16.8M$13.8M$49.8M
FY2022——−$59.6M−$58.4M−$1.38−$52.5M$272K$74.5M$8.1M$66.3M$7.6M—
FY2021——−$43.1M−$42.9M−$1.02−$33.2M—$119.8M$7.2M$112.6M$114.1M—
FY2020——−$50.7M−$50.0M−$1.70−$50.7M—$150.0M$6.9M$143.1M$72.3M—
FY2019——−$57.9M−$55.2M−$3.50−$51.2M$413K$123.4M$8.5M$114.9M$119.8M$0
FY2018——−$23.8M−$23.2M$72.63−$21.0M$5K$88.1M$4.5M$83.5M$85.9M—
FY2017—————————$26.0M$10.9M—

Latest filings

the most recent regulatory filings
8-KCurrent report — material event2026-06-15 ↗4Insider ownership filing2026-06-12 ↗4Insider ownership filing2026-06-12 ↗4Insider ownership filing2026-06-12 ↗4Insider ownership filing2026-06-12 ↗4Insider ownership filing2026-06-12 ↗4Insider ownership filing2026-06-12 ↗4Insider ownership filing2026-06-12 ↗EFFECTSEC filing2026-05-22 ↗SCHEDULE 13G/ASEC filing2026-05-15 ↗

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